The Apothecary Diaries Season 3 Trailer Reveals Ending Theme Song

TOHO animation just released a brand new trailer for the third season of the anime adaptation of Hyuganatsu and Touko Shino’s The Apothecary Diaries (Kusuriya no Hitorigoto) light novel series. The video reveals the ending theme song “AIYOU,” which will be performed by Eve.

Reina Ueda joins the cast this season as Bai Niangniang. Akinori Fudesaka will direct The Apothecary Diaries Season 3 at animation studio OLM, with Wataru Nakagawa serving as assistant director. Norihiro Naganuma will handle the series composition, while Yuko Kakkihara, Misuzu Chiba, and Hitomi Ogawa will handle the series scripts.

Yukiko Nakatani will handle the character designs. Satoru Kosaki, Kevin Penkin, and Arisa Okehazama will compose the music. yorushika will perform the opening theme song “Kumo o Nukekazashimo e Watashidake” (I Am Alone, Breaking Through the Clouds Downwind).

Natsu Hyuga writes the original The Apothecary Diaries light novel series, with illustrations by Toko Shino. The novel made its debut on the Shōsetsuka ni Narō website in October 2011. Nekokurage later launched an ongoing manga adaptation in Square Enix’s Monthly Big Gangan magazine in May 2017.

The Apothecary Diaries Season 2 ran from January 10 to July 4, 2025, and is streaming on Crunchyroll. What’s more, Itsuki Nanao’s The Apothecary Diaries: Xiaolan’s Story manga launched on Manga UP! on March 23.

Lastly, here’s a synopsis of the series, via Crunchyroll:

Maomao lived a peaceful life with her apothecary father until one day, she’s sold as a lowly servant to the emperor’s palace. But she wasn’t meant for a compliant life among royalty. So when imperial heirs fall ill, she decides to step in and find a cure! This catches the eye of Jinshi, a handsome palace official who promotes her. Now, she’s making a name for herself solving medical mysteries!